Plasma Drug Level Validates Self-Reported Adherence but Predicts Limited Specificity for Nonadherence to Antiretroviral Therapy

Table 2

Multivariate models explaining the association between plasma drug therapeutic concentrations and self-report adherence adjusted for demographic/clinical characteristics among patients on a stavudine-containing regimen in Uganda.

Adjusting variable	Adjusted association between plasma drug concentration and self-reported adherence
	Adjusted odds ratio (95% CI)	𝑃-value
None [crude association]	6.72 (3.06, 14.78)	<0.0001
Gender	7.13 (3.18, 16.01)	<0.0001
Age in years	6.72 (3.22, 14.01)	<0.0001
Employment status	6.54 (2.92, 14.65)	<0.0001
Marital status	6.56 (2.98, 14.41)	<0.0001
Education	6.75 (3.06, 14.87)	<0.0001
Alcohol drinking status	6.94 (3.10, 15.52)	<0.0001
Current CD4 count in cells/mL	7.34 (3.39, 15.87)	<0.0001
Body weight in kgs	8.49 (3.21, 22.46)	<0.0001