Research Article

N-Aryl Lactams by Regioselective Ozonation of N-Aryl Cyclic Amines

Table 2

Synthesis of -aryl-lactams by ozonation of - -polymethylene-anilines.

EntryaSubstrateConversionbProductYield %c

1281642.table.001a68%281642.table.001b52

2281642.table.002a70%281642.table.002b63

3281642.table.003a74%281642.table.003b71

4281642.table.004a20%281642.table.004b18

aFor the condition see the experimental part.
bConversions are calculated on the recovered starting material.
cIsolated yield after silica gel chromatography.