Table of Contents
ISRN Obstetrics and Gynecology
Volume 2012, Article ID 286141, 8 pages
Research Article

Comparison of Fetal Cerebellum and Cisterna Magna Length by 2D and 3D Ultrasonography between 18 and 24 Weeks of Pregnancy

1Department of Obstetrics and Gynecology, Medical Science College of Santa Casa of São Paulo (FCMSCSP), 05303-000 São Paulo, SP, Brazil
2Department of Obstetrics, Federal University of São Paulo (UNIFESP), 05303-000 São Paulo, SP, Brazil

Received 13 August 2012; Accepted 8 October 2012

Academic Editors: K. Chan and H. Rehder

Copyright © 2012 Fernanda Silveira Bello de Barros et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


To compare the fetal cerebellum and cisterna magna length measurements by means of two- (2DUS) and three-dimensional (3DUS) ultrasonography using the three-dimensional extended imaging (3D XI), a cross-sectional study with 69 healthy pregnant women between 18 and 24 weeks was performed. For the measurements by 2DUS, the axial planes were used and for the 3DUS a sequence of adjacent axial slices (multislice view). To evaluate the difference between the two techniques, we used the Wilcoxon test. To evaluate the correlation between the cerebellum and cisterna magna length measurements and the gestational age, we used the Spearman correlation coefficient ( ). For the calculation of reproducibility, we used the intraclass correlation coefficient (ICC). The mean of the transverse and anterior-posterior diameter of cerebellum and cisterna magna by 3DUS was 9.23 and 6.62 mm, respectively. It was observed that the average of the measurements obtained by 3DUS was significantly higher, 0.76 and 1.02 mm for the length of the cerebellum and cisterna magna, respectively ( ). There was a high correlation between the length measurement of the cerebellum 3D ( , ), but low correlation of cisterna magna 3D ( , ) with the gestational age. There was good intra- and interobserver reproducibility for the cerebellum and cisterna magna 3D with , 0.668, 0.691, and 0.287, respectively. The measurements of the fetal cerebellum and cisterna magna length by 3DUS using the software 3D XI were significantly higher than those obtained by 2DUS.