Research Article

Mathematical Behavior of MEFV Curves in Childhood Asthma and the Role of Curvature in Quantifying Flow Obstruction

Figure 7

Example of a patient with a distinct quasilinear profile in the descending phase of the MEFV curve. (a) Plot of second derivative, 𝑑 2 ̇ 𝑉 / 𝑑 𝑉 2 , as a function of expired volume V. (b) MEFV curve with (--) resulting quadratic fit and (o) IP. Steady-state value of the second derivative, 𝑑 2 ̇ 𝑉 / 𝑑 𝑉 2 , and ACI are, respectively, given in (a) and (b).
305176.fig.007a
(a)
305176.fig.007b
(b)