Menadione : Sodium Orthovanadate Combination Eliminates and Inhibits Migration of Detached Cancer Cells
Figure 2
Long-term antiproliferative effect of menadione (M), sodium orthovanadate (SO), and M : SO combination. The combined treatment with M : SO reduced the needed concentration of each agent to kill 100% of A549 lung cancer cells preventing regrowth (RC0) after 7 days. The figure shows the schematic representation of events in a single well. Top panel: cells exposed to increasing concentrations (1–50 μM) of M or SO alone. Bottom panel: combined treatment with M : SO reaches RC0 (17.5 μM : 17.5 μM). Table: effect of M : SO at different concentrations and exposure time. (+) indicates regrowth observed in at least one well. (−) indicates no regrowth observed.
