Malignant Melanoma

Table 1

TNM staging.

Primary tumour staging (T)
Tx	Primary tumour is not identify
Tis	In situ melanoma
T1	≤1.00 mm
T1a	Without ulceration, without mitosis
T1b	With ulceration or mitotic rate ≥ 1 mm^2
T2	1.01–2.00 mm
T2a	Without ulceration
T2b	With ulceration
T3	2.01–4.00 mm
T3a	Without ulceration
T3b	With ulceration
T4	>4.00 mm
T4a	Without ulceration
T4b	With ulceration
Lymph node status (N)
N1	One node involved
N1a	Micrometastases
N1b	Macrometastases
N2	Two or Three nodes affected
N2a	Micrometastases
N2b	Macrometastases
N2c	Intransit metastases/satellites without metastatic nodes
N3	Four or more nodes or matted nodes or intransist metastases/satellites with metastastic nodes
Distant metastases (M)
M1a	Distant skin, subcutaneous or nodal metastases with normal LHD levels
M1b	Lung metastases with normal LDH levels
M1c	All over visceral metastases or any distant metastases with elevated LDH levels