Table of Contents
ISRN Neurology
Volume 2012, Article ID 320607, 7 pages
http://dx.doi.org/10.5402/2012/320607
Clinical Study

The Effect of Pramipexole Therapy on Balance Disorder and Fall Risk in Parkinson’s Disease at Early Stage: Clinical and Posturographic Assessment

1Department of Neurology, Faculty of Medicine, Trakya University, 22030 Edirne, Turkey
2Department of Neurology, Faculty of Medicine, Pamukkale University, 20070 Denizli, Turkey
3Department of Biostatistics, Faculty of Medicine, Pamukkale University, 20070 Denizli, Turkey
4Department of Physical Treatment and Rehabilitation, Faculty of Medicine, Pamukkale University, 20070 Denizli, Turkey

Received 3 April 2012; Accepted 5 June 2012

Academic Editors: D. Dewar and B. Drukarch

Copyright © 2012 Sibel Güler et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. W. Błaszczyk, R. Orawiec, D. Duda-Kłodowska, and G. Opala, “Assessment of postural instability in patients with Parkinson's disease,” Experimental Brain Research, vol. 183, no. 1, pp. 107–114, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. F. Stanley and J. Jankovic, Movement Disorders, Data Medical Publishing, Ankara, Turkey, 2008.
  3. J. Jankovich, “Pathophysiology and clinical assessment of parkinsonian symptoms and signs,” in Handbook of Parkinson’s Disease, R. Pahta, K. E. Lyons, and W. C. Koller, Eds., pp. 71–107, Marcel Dekker, New York, NY, USA, 2003. View at Google Scholar
  4. S. Ertan, “The clinical features of Parkinson's disease,” Continuous Medical Education at the Faculty of Medicine, vol. 42, pp. 249–254, 2005. View at Google Scholar
  5. L. S. Forno, “Neuropathology of Parkinson's disease,” Journal of Neuropathology and Experimental Neurology, vol. 55, no. 3, pp. 259–272, 1996. View at Google Scholar · View at Scopus
  6. C. Adler and J. E. Ahlskog, Parkinson’s Disease and Movement Disorders, Current Clinical Practice, Humana Press, Totowa, NJ, USA, 2000.
  7. H. Apaydın, “Alpha-synuclein diseases,” Parkinson's Disease and Movement Disorders Journal, vol. 2, pp. 23–30, 1999. View at Google Scholar
  8. F. Smithson, M. E. Morris, and R. Iansek, “Performance on clinical tests of balance in Parkinson's disease,” Physical Therapy, vol. 78, no. 6, pp. 577–592, 1998. View at Google Scholar · View at Scopus
  9. J. P. Bennett and M. F. Piercey, “Pramipexole–a new dopamine agonist for the treatment of Parkinson's disease,” Journal of the Neurological Sciences, vol. 163, no. 1, pp. 25–31, 1999. View at Publisher · View at Google Scholar · View at Scopus
  10. C. W. Olanow, K. Kieburtz, and A. H. V. Schapira, “Why have we failed to achieve neuroprotection in Parkinson's disease?” Annals of Neurology, vol. 64, no. 2, pp. S101–S110, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Visser, J. Marinus, B. R. Bloem, and H. Kisijes, “Clinical tests for thevaluationof postural instability in patients with Parkinson’s Disease,” Archives of Physical Medicine and Rehabilitation, vol. 84, pp. 1669–1674, 2003. View at Google Scholar
  12. K. S. Wong, C. S. Lu, D. E. Shan, C. C. Yang, T. H. Tsoi, and V. Mok, “Efficacy, safety, and tolerability of pramipexole in untreated and levodopa-treated patients with Parkinson's disease,” Journal of the Neurological Sciences, vol. 216, no. 1, pp. 81–87, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. A. A. Qutubuddin, P. O. Pegg, D. X. Cifu, R. Brown, S. McNamee, and W. Carne, “Validating the Berg Balance Scale for patients with Parkinson's disease: a key to rehabilitation evaluation,” Archives of Physical Medicine and Rehabilitation, vol. 86, no. 4, pp. 789–792, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. Y. Balash, C. Peretz, G. Leibovich, T. Herman, J. M. Hausdorff, and N. Giladi, “Falls in outpatients with Parkinson's disease: frequency, impact and identifying factors,” Journal of Neurology, vol. 252, no. 11, pp. 1310–1315, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. R. Marchese, M. Bove, and G. Abbruzzese, “Effect of cognitive and motor tasks on postural stability in Parkinson's disease: a posturographic study,” Movement Disorders, vol. 18, no. 6, pp. 652–658, 2003. View at Publisher · View at Google Scholar · View at Scopus
  16. J. G. Ouslander, D. Osterweil, and J. Morley, “Gait disorders and gait,” in Medical Care in the Nursing Home, J. G. Ouslander, D. Osterweil, and J. Morley, Eds., pp. 251–275, McGraw-Hill, New York, NY ,USA, 1997. View at Google Scholar
  17. K. B. Gunter, K. N. White, W. C. Hayes, and C. M. Snow, “Functional mobility discriminates nonfallers from one-time and frequent fallers,” Journals of Gerontology A, vol. 55, no. 11, pp. M672–M676, 2000. View at Google Scholar · View at Scopus
  18. M. Schenkman, T. M. Cutson, M. Kuchibhatla, J. Chandler, and C. Pieper, “Reliability of impairment and physical performance measures for persons with Parkinson's disease,” Physical Therapy, vol. 77, no. 1, pp. 19–27, 1997. View at Google Scholar · View at Scopus
  19. S. Morris, M. E. Morris, and R. Iansek, “Reliability of measurements obtained with the Timed “Up, & Go” Test in people with Parkinson disease,” Physical Therapy, vol. 81, no. 2, pp. 810–818, 2001. View at Google Scholar · View at Scopus
  20. A. Shumway-Cook, M. Baldwin, N. L. Polissar, and W. Gruber, “Predicting the probability for falls in community-dwelling older adults,” Physical Therapy, vol. 77, no. 8, pp. 812–819, 1997. View at Google Scholar · View at Scopus
  21. N. Chastan, B. Debono, D. Maltête, and J. Weber, “Discordance between measured postural instability and absence of clinical symptoms in Parkinson's disease patients in the early stages of the disease,” Movement Disorders, vol. 23, no. 3, pp. 366–372, 2008. View at Publisher · View at Google Scholar · View at Scopus
  22. Y. Salık, K. Bilge, D. Ç. Beril, and R. Çakmur, “Measuring the factors effecting on falling risk in patients with Parkinson’s disease,” Parkinson's Disease and Movement Disorders Journal, vol. 10, pp. 35–41, 2007. View at Google Scholar
  23. R. P. Di Fabio, “Sensitivity and specificity of platform posturography for identifying patients with vestibular dysfunction,” Physical Therapy, vol. 75, no. 4, pp. 290–305, 1995. View at Google Scholar · View at Scopus