Table of Contents
ISRN Vascular Medicine
Volume 2012, Article ID 341763, 10 pages
http://dx.doi.org/10.5402/2012/341763
Clinical Study

Metabolic Profiling of Patients Undergoing Elective Aortic Aneurysm Repair Surgery: Correlation with Anaerobic Threshold

1School of Chemistry, University of Leeds, Leeds LS2 9JT, UK
2Leeds Institute of Molecular Medicine, University of Leeds, Leeds LS9 7TF, UK
3Leeds Vascular Institute, Leeds General Infirmary, Leeds LS1 3EX, UK

Received 10 August 2012; Accepted 13 September 2012

Academic Editors: J. E. Nordrehaug and A. Suzuki

Copyright © 2012 Cassey McRae et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Figure S1, which shows the PCA scores and 1D loadings line plots built from the preoperative spectral data only. These plots show a difference in the plasma metabolic profiles between patients with high and low AT even before surgery; Table S1 reports the spectral bins (and hence metabolites) responsible for separating the preoperative and postoperative plasma samples in the PCA scores plots in Figure 1 of the main text; Finally, Figure S2 shows the scores and 1D loadings line plots for the predictive component of an OPLS model created using the postoperative spectral data normalised to the preoperative data regressed against the AT values of the patients, where AT was considered a continuous variable, rather than using the cut off “high” and “low” AT values as in the main text.

  1. Supplementary Materials