International Scholarly Research Notices

Clinical Study

Morbidity and Quality of Life in Bladder Cancer Patients following Cystectomy and Urinary Diversion: A Single-Institution Comparison of Ileal Conduit versus Orthotopic Neobladder

Table 3

QLQ-C30.
QLQ-C30Ileal conduit
Mean ± standard dev.
Median (interquartile range)
𝑛 = n u m b e r of cases		Ileal neobladder
Mean ± standard dev.
Median (interquartile range)
𝑛 = n u m b e r of cases
Functional scales
Global health status/quality of lifea 5 8 . 0 ± 2 5 . 3 7 2 . 3 ± 1 9 . 5
58.3 (33.3–83.3)70.8 (56.2–85.4)
𝑛 = 2 3 𝑛 = 3 4
Physical functioningb 6 5 . 8 ± 2 9 . 4 8 2 . 6 ± 1 9 . 9
70 (33.3–93.3)93.3 (71.6–100)
𝑛 = 2 4 𝑛 = 3 4
Role functioning 6 3 . 8 ± 3 1 . 1 7 6 . 0 ± 2 7 . 9
66.7 (33.3–100)83.3 (50–100)
𝑛 = 2 4 𝑛 = 3 4
Emotion functioning 7 2 . 2 ± 2 2 . 3 8 1 . 1 ± 2 2 . 3
70.8 (52.1–91.7)87.5 (66.7–100)
𝑛 = 2 4 𝑛 = 3 4
Cognitive functioning 7 7 . 8 ± 2 2 . 9 8 3 . 3 ± 2 0 . 5
83.3 (54.2–100)83.3 (66.7–100)
𝑛 = 2 4 𝑛 = 3 4
Social functioning 6 5 . 3 ± 3 2 . 2 7 0 . 1 ± 3 3 . 0
83.3 (33.3–95.8)75 (45.8–100)
𝑛 = 2 4 𝑛 = 3 4
Symptoms scales
Fatigue 3 7 . 5 ± 2 8 . 1 2 6 . 0 ± 2 8 . 3
33.3 (11.1–63.9)16.7 (0–55.6)
𝑛 = 2 4 𝑛 = 3 4
Nausea and vomiting 9 . 7 ± 2 0 . 2 3 . 4 ± 1 2 . 8
0 (0–12.5)0 (0-0)
𝑛 = 2 4 𝑛 = 3 4
Pain 2 6 . 4 ± 3 1 . 8 1 8 . 6 ± 3 4 . 0
8.3 (0–50)0 (0–33.3)
𝑛 = 2 4 𝑛 = 3 4
Single items
Dyspnoea 3 7 . 5 ± 3 5 . 9 2 7 . 5 ± 3 7 . 1
33 (0–66.7)0 (0–41.7)
𝑛 = 2 4 𝑛 = 3 4
Insomnia 2 9 . 2 ± 3 1 . 6 2 1 . 6 ± 2 7 . 1
33.3 (0–66.7)0 (0–33.3)
𝑛 = 2 4 𝑛 = 3 4
Appetite loss 1 8 . 1 ± 3 1 . 1 6 . 9 ± 1 7 . 9
0 (0–33.3)0 (0-0)
𝑛 = 2 4 𝑛 = 3 4
Constipation 2 2 . 2 ± 3 0 . 6 1 1 . 8 ± 1 9 . 9
0 (0–33.3)0 (0–33.3)
𝑛 = 2 4 𝑛 = 3 4
Diarrhoeac 4 . 2 ± 1 4 . 9 2 3 . 5 ± 3 1 . 3
0 (0-0)0 (0–33.3)
𝑛 = 2 4 𝑛 = 3 4
Financial difficulties 2 5 . 0 ± 3 5 . 8 2 0 . 6 ± 3 2 . 8
0 (0–66.7)0 (0–41.7)
𝑛 = 2 4 𝑛 = 3 4
at-test; 𝑃 = 0 . 0 1 9 .
bU test; 𝑃 = 0 . 0 1 8 .
cU test; 𝑃 = 0 . 0 0 4 .
EORTC QLQ-C30 results of this study. The questionnaire assesses cancer-specific QOL. For all the questions, a scale from 1 to 4 was used (1: not at all, 2: a little, 3: quite a bit, 4: very much). All scores were linearly transformed such that all scales range from 0 to 100. For the six functional items, the higher score represents a higher level of functioning and for the symptoms/single items, a higher score means a higher level of symptomatology/problems.