Table of Contents
ISRN Minimally Invasive Surgery
Volume 2012 (2012), Article ID 364285, 9 pages
http://dx.doi.org/10.5402/2012/364285
Research Article

High-Resolution Optical Imaging of Benign and Malignant Mucosa in the Upper Aerodigestive Tract: An Atlas for Image-Guided Surgery

1Department of Otolaryngology-Head and Neck Surgery, Mount Sinai School of Medicine, New York, NY 10029, USA
2Department of Bioengineering, Rice University, Houston, TX 77030, USA
3Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029, USA
4Division of Gastroenterology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
5Division of Surgery, Head & Neck Surgery Department, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA

Received 18 June 2012; Accepted 9 July 2012

Academic Editors: M. Barczyński and K. J. Dedes

Copyright © 2012 Lauren L. Levy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. A. Brennan, L. Mao, R. H. Hruban et al., “Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck,” The New England Journal of Medicine, vol. 332, no. 7, pp. 429–435, 1995. View at Publisher · View at Google Scholar · View at Scopus
  2. R. Haque, R. Contreras, M. P. McNicoll, E. C. Eckberg, and D. B. Petitti, “Surgical margins and survival after head and neck cancer surgery,” BMC Ear, Nose and Throat Disorders, vol. 6, article 2, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Gamba, M. Romano, I. M. Grosso et al., “Psychosocial adjustment of patients surgically treated for head and neck cancer,” Head and Neck, vol. 14, no. 3, pp. 218–223, 1992. View at Google Scholar · View at Scopus
  4. M. J. Dropkin, “Body image and quality of life after head and neck cancer surgery,” Cancer Practice, vol. 7, no. 6, pp. 309–313, 1999. View at Publisher · View at Google Scholar · View at Scopus
  5. C. Black, J. Marotti, E. Zarovnaya, and J. Paydarfar, “Critical evaluation of frozen section margins in head and neck cancer resections,” Cancer, vol. 107, no. 12, pp. 2792–2800, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. L. J. DiNardo, J. Lin, L. S. Karageorge, and C. N. Powers, “Accuracy, utility, and cost of frozen section margins in head and neck cancer surgery,” Laryngoscope, vol. 110, no. 10, pp. 1773–1776, 2000. View at Google Scholar · View at Scopus
  7. R. A. Ord and S. Aisner, “Accuracy of frozen sections in assessing margins in oral cancer resection,” Journal of Oral and Maxillofacial Surgery, vol. 55, no. 7, pp. 663–671, 1997. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Keereweer, H. J. C. M. Sterenborg, J. D. F. Kerrebijn, P. B. A. A. Van Driel, R. J. B. De Jong, and C. W. G. M. Löwik, “Image-guided surgery in head and neck cancer: current practice and future directions of optical imaging,” Head and Neck, vol. 34, pp. 120–126, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. D. Roblyer, R. Richards-Kortum, K. Sokolov et al., “Multispectral optical imaging device for in vivo detection of oral neoplasia,” Journal of Biomedical Optics, vol. 13, no. 2, Article ID 024019, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. D. Roblyer, C. Kurachi, V. Stepanek et al., “Objective detection and delineation of oral neoplasia using autofluorescence imaging,” Cancer Prevention Research, vol. 2, no. 5, pp. 423–431, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. C. F. Poh, L. Zhang, D. W. Anderson et al., “Fluorescence visualization detection of field alterations in tumor margins of oral cancer patients,” Clinical Cancer Research, vol. 12, no. 22, pp. 6716–6722, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. T. J. Muldoon, D. Roblyer, M. D. Williams, V. M. T. Stepanek, R. Richards-Kortum, and A. M. Gillenwater, “Noninvasive imaging of oral neoplasia with a high-resolution fiber-optic microendoscope,” Head and Neck, vol. 34, no. 3, pp. 305–312, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. A. L. Clark, A. M. Gillenwater, T. G. Collier, R. Alizadeh-Naderi, A. K. El-Naggar, and R. R. Richards-Kortum, “Confocal microscopy for real-time detection of oral cavity neoplasia,” Clinical Cancer Research, vol. 9, no. 13, pp. 4714–4721, 2003. View at Google Scholar · View at Scopus
  14. A. Clark, T. Collier, A. Lacy et al., “Detection of dysplasia with near real time confocal microscopy,” Biomedical Sciences Instrumentation, vol. 38, pp. 393–398, 2002. View at Google Scholar · View at Scopus
  15. C. F. Poh, C. E. MacAulay, L. Zhang, and M. P. Rosin, “Tracing the “at-risk” oral mucosa field with autofluorescence: steps toward clinical impact,” Cancer Prevention Research, vol. 2, no. 5, pp. 401–404, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. C. F. Poh, J. S. Durham, P. M. Brasher et al., “Canadian Optically-guided approach for Oral Lesions Surgical (COOLS) trial: study protocol for a randomized controlled trial,” BMC Cancer, vol. 11, article 462, Article ID 462, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. A. L. Clark, A. M. Gillenwater, T. G. Collier, R. Alizadeh-Naderi, A. K. El-Naggar, and R. R. Richards-Kortum, “Confocal microscopy for real-time detection of oral cavity neoplasia,” Clinical Cancer Research, vol. 9, no. 13, pp. 4714–4721, 2003. View at Google Scholar · View at Scopus
  18. M. W. White, M. Rajadhyaksha, S. González, R. L. Fabian, and R. R. Anderson, “Noninvasive imaging of human oral mucosa in vivo by confocal reflectance microscopy,” Laryngoscope, vol. 109, no. 10, pp. 1709–1717, 1999. View at Publisher · View at Google Scholar · View at Scopus
  19. T. J. Muldoon, S. Anandasabapathy, D. Maru, and R. Richards-Kortum, “High-resolution imaging in Barrett's esophagus: a novel, low-cost endoscopic microscope,” Gastrointestinal Endoscopy, vol. 68, no. 4, pp. 737–744, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. K. J. Rosbach, D. Shin, T. J. Muldoon et al., “High-resolution fiber optic microscopy with fluorescent contrast enhancement for the identification of axillary lymph node metastases in breast cancer: a pilot study,” Biomedical Optics Express, vol. 1, pp. 911–922, 2010. View at Google Scholar
  21. T. J. Muldoon, D. Roblyer, M. D. Williams, V. M. T. Stepanek, R. Richards-Kortum, and A. M. Gillenwater, “Noninvasive imaging of oral neoplasia with a high-resolution fiber-optic microendoscope,” Head and Neck, vol. 34, no. 3, pp. 305–312, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. P. Vila, C. Park, M. Pierce et al., “Discrimination of benign and neoplastic mucosa with a high-resolution microendoscope (HRME) in head and neck cancer,” Annals of Surgical Oncology. In press.
  23. T. J. Muldoon, M. C. Pierce, D. L. Nida, M. D. Williams, A. Gillenwater, and R. Richards-Kortum, “Subcellular-resolution molecular imaging within living tissue by fiber microendoscopy,” Optics Express, vol. 15, no. 25, pp. 16413–16423, 2007. View at Google Scholar · View at Scopus
  24. L. R. Ferguson and W. A. Denny, “Genotoxicity of non-covalent interactions: DNA intercalators,” Mutation Research, vol. 623, no. 1-2, pp. 14–23, 2007. View at Publisher · View at Google Scholar · View at Scopus
  25. A. L. Polglase, W. J. McLaren, S. A. Skinner, R. Kiesslich, M. F. Neurath, and P. M. Delaney, “A fluorescence confocal endomicroscope for in vivo microscopy of the upper- and the lower-GI tract,” Gastrointestinal Endoscopy, vol. 62, no. 5, pp. 686–695, 2005. View at Publisher · View at Google Scholar · View at Scopus
  26. R. Kiesslich, J. Burg, M. Vieth et al., “Confocal laser endoscopy for diagnosing intraepithelial neoplasias and colorectal cancer in vivo,” Gastroenterology, vol. 127, no. 3, pp. 706–713, 2004. View at Publisher · View at Google Scholar · View at Scopus
  27. P. A. Janssen, B. L. Selwood, S. R. Dobson, D. Peacock, and P. N. Thiessen, “To dye or not to dye: a randomized, clinical trial of a triple dye/alcohol regime versus dry cord care,” Pediatrics, vol. 111, no. 1, pp. 15–20, 2003. View at Publisher · View at Google Scholar · View at Scopus
  28. E. M. Genden, S. Desai, and C. K. Sung, “Transoral robotic surgery for the management of head and neck cancer: a preliminary experience,” Head and Neck, vol. 31, no. 3, pp. 283–289, 2009. View at Publisher · View at Google Scholar · View at Scopus