Clinical Study
Evaluation of the Immune Response of Individuals Infected with Mycobacterium tuberculosis and Patients with Active Tuberculosis
Table 1
Comparison of the results of the immunological tests by group.
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*Chi-squared test, **Fisher’s test. IgG levels determined by ELISA in the plasma of healthy individuals (Group A), of LTBI (Group B), and patients with active tuberculosis (Group C). Calculation of the stimulation index (SI) obtained after testing the lymph proliferative assay (LPA) after PBMC stimulation with BCG for 72 hours. Measurement of the cytokine levels (IFN-γ, TNF-α, and IL-10) obtained from the supernatant of a PBMC culture from individuals from Groups A, B, and C after stimulation for 72 hours with BCG. The median represents the absorbance obtained by the ELISA reaction for IgG levels in plasma and cytokines in supernatants of PBMC cultures stimulated with BCG. However, in the LPA, the median signifies the SI. |