Docking Applied to the Study of Inhibitors of c-Met Kinase
Top view of the active site of the kinase with the docking solutions for compounds 27 (carbon atoms in orange) and 31 (carbon atoms in pink). Distances between O atoms of the ligands and N atom of ASP1222 were measured for both compounds. Color code for heteroatoms is as follows: fluorine: cyan, nitrogen: blue, sulfur: yellow, and oxygen: red. Only one hydrogen atom of MET1160 was shown for simplicity.
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