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ISRN Analytical Chemistry
Volume 2012 (2012), Article ID 401702, 4 pages
Research Article

Simultaneous Estimation of Lafutidine and Domperidone by Ultraviolet Spectroscopy

1Department of Pharmaceutical Analysis, Genba Sopanrao Moze College of Pharmacy, Wagholi, Maharashtra, Pune 412207, India
2Department of Formulation and Development, Alkem Laboratories Ltd., Panvel 410208, India

Received 23 March 2012; Accepted 23 April 2012

Academic Editors: D. J. Fletouris and D. Patra

Copyright © 2012 Kiran Jadhav et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A simple, accurate, and precise method for simultaneous estimation of Lafutidine and Domperidone in combined-dosage form have been described. The method employs formation and solving of simultaneous equations using 279 and 284 nm as two analytical wavelengths. This method allows the simultaneous determination of Lafutidine and Domperidone in concentration ranges employed for this purpose with the standard deviation of <1.0% in the assay of tablet.