Modeling, Analysis, and Intelligent Controller Tuning for a Bioreactor: A Simulation Study

Table 1

Nominal parameters of bioreactor.

Parameter		Values
𝑋𝑠		0; g/lit—lag phase
	Biomass concentration	0.9951; g/lit—growth phase
		1.5302; g/lit—stationary phase
𝑆𝑠		4.0; g/lit—lag phase
	Substrate concentration	1.5122; g/lit—growth phase
		0.1746; g/lit—stationary phase
𝐷	Dilution rate	0.3; hr^−1
𝑋𝑓𝑠	Feed substrate concentration	4.0 g/lit
𝜇max	Maximum specific growth rate	0.53; hr^−1
𝐾𝑚	Substrate saturation constant	0.12; g/lit
𝑌	Cell mass yield	0.4
𝐾1	Substrate inhibition constant	0.4545; lit/g
𝑋(0)	Initial arbitrary value of biomass (for simulation study)	0; g/lit—lag phase
		0.125; g/lit—growth phase
		1; g/lit—stationary phase
𝑆(0)	Initial arbitrary value of substrate (for simulation study)	1; g/lit—lag phase
		1; g/lit—growth phase
		1; g/lit—stationary phase
α, β	Yield parameters for the product—to be selected based on the substrate and biomass
	(it will have value only during the real time study)