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ISRN Rheumatology
Volume 2012 (2012), Article ID 428269, 6 pages
Review Article

Thrombosis in Systemic Lupus Erythematosus: A Review Article

College of Medicine, Imam Muhammad Ibn Saud Islamic University, P.O. Box 75227, Riyadh 11578, Saudi Arabia

Received 19 April 2012; Accepted 20 June 2012

Academic Editors: M. G. Danieli, J. Ioannou, G. Murdaca, and B. Ongphiphadhanakul

Copyright © 2012 Ibrahim A. Al-Homood. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Thrombosis is a well-known clinical entity in systemic lupus erythematosus (SLE), and it is multifactorial. The most important risk factor is the presence of antiphospholipid antibodies (APLAs). However, approximately 40% of adults with SLE who are negative for APL A are diagnosed with thrombosis, indicating the importance of other risk factors. Thus, the thrombosis risk factors should be evaluated extensively and regularly and treated aggressively in every patient with systemic lupus erythematosus.