Development and Evaluation of Sustained Release Tablet of Betahistine Hydrochloride Using Ion Exchange Resin Tulsion T344

Table 1

Formulation of tablets.

Ingredients	Batch
	T1	T2	T3	T4	T5
Tulsion T344 resinate	118^*	118^*	118^*	118^*	118^*
Microcrystalline cellulose	117	92	87	82	77
HPMC K100M	—	25	30	35	40
PVP K30	7	7	7	7	7
Mg stearate	3	3	3	3	3
Talc	5	5	5	5	5

^*DRC containing 24 mg Betahistine and total weight of tablet is 250 mg.