Table of Contents
ISRN Neurology
Volume 2012, Article ID 452703, 5 pages
Clinical Study

Polyetheretherketone Cages Alone with Allograft for Three-Level Anterior Cervical Fusion

1Department of Orthopaedics, Peking University First Hospital, Beijing 100034, China
2Division of Orthopaedics and Rehabilitation, Department of Surgery, Ioannina University Medical School, 45110 Ioannian, Greece

Received 8 October 2011; Accepted 31 October 2011

Academic Editor: A. Lagares

Copyright © 2012 Hong Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A total of 25 consecutive patients suffering from degenerative cervical disc disease who underwent three-level anterior cervical discectomy and fusion (ACDF) including polyetheretherketone (PEEK) cages packed with allograft were followed up for at least two years. The fusion rate reached 72% (18/25), and asymptomatic pseudarthrosis was seen in 6 patients but without mobility on flexion-extension radiographs, and revision surgery was not needed. Cage subsidence occurred at one level (C67), but it was not progressive, and reoperation was not necessary. A significant increase ( 𝑃 < 0 . 0 0 1 ) in fused segment angle (FSA) and fused segment height (FSH) was observed postoperatively. Similarly, a significant clinical improvement ( 𝑃 < 0 . 0 0 1 ) was demonstrated postoperatively in terms of Japanese Orthopedic Association (JOA) score and visual analog scales (VASs) score. PEEK cages alone with allograft proved to be a safe and effective surgical option in the treatment of three-level degenerative cervical disc disease. Although the fusion rate was not high, this technique may offer improvement of symptomatology and maintenance of cervical spine's sagittal profile.