Table of Contents
ISRN Ophthalmology
Volume 2012, Article ID 456209, 7 pages
Review Article

Exogenous Endophthalmitis in Diabetic Patients: A Systemic Review

The Department of Ophthalmology, American University of Beirut Medical Center, P.O. Box 11-0236, Beirut 1107 2020, Lebanon

Received 2 August 2012; Accepted 26 August 2012

Academic Editors: N. Ardjomand and I. J. Wang

Copyright © 2012 Georges M. El-Mollayess et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Diabetes mellitus is a systemic disease that increases the risk of infections. Exogenous endophthalmitis is an inflammatory disease to which diabetic patients are more predisposed to than nondiabetic patients undergoing any intraocular intervention. This might be because of the change in the immune and inflammatory factors that intervene in wound healing and in the bacterial flora of the ocular adnexa. We conducted a literature review to assess the risk of exogenous endophthalmitis in diabetic patients undergoing cataract extraction, pars plana vitrectomy, and intravitreal injections and to check whether its treatment differ from in non-diabetics. We found that diabetic patients are more predisposed to virulent organisms and that the incidence of ophthalmic symptoms was not substantially different in diabetic versus nondiabetic patients. Regarding treatment, all patients with light perception should receive pars plana vitrectomy, while those with hand motion and better vision should be given an intravitreal antibiotics injection. Some authors recommend vitrectomy to diabetic patients with even counting figure vision.