Review Article

Antioncogenic Effects of Transient Receptor Potential Vanilloid 1 in the Progression of Transitional Urothelial Cancer of Human Bladder

Figure 2

Capsaicin induces clustering and colocalization of Fas/CD95 and TRPV1 in RT4 UCCs. The immunocytochemical localization of Fas/CD95 and TRPV1 in UCCs treated with capsaicin was analyzed by confocal microscopy using an anti-Fas/CD95 mAb and a goat anti-TRPV1 Ab followed by respective secondary Abs. Merge panel indicates overlapping between Fas/CD95 and TRPV1 proteins. Bar = 10 μm.
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