Table of Contents
ISRN Pharmaceutics
Volume 2012 (2012), Article ID 474830, 14 pages
http://dx.doi.org/10.5402/2012/474830
Review Article

Lipoidal Soft Hybrid Biocarriers of Supramolecular Construction for Drug Delivery

Department of Pharmaceutics, CT Institute of Pharmaceutical Sciences, Jalandhar 144020, India

Received 27 March 2012; Accepted 3 May 2012

Academic Editors: M. Li and M. Moneghini

Copyright © 2012 Dinesh Kumar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Lipid-based innovations have achieved new heights during the last few years as an essential component of drug development. The current challenge of drug delivery is liberation of drug agents at the right time in a safe and reproducible manner to a specific target site. A number of novel drug delivery systems has emerged encompassing various routes of administration, to achieve controlled and targeted drug delivery. Microparticulate lipoidal vesicular system represents a unique technology platform suitable for the oral and systemic administration of a wide variety of molecules with important therapeutic biological activities, including drugs, genes, and vaccine antigens. The success of liposomes as drug carriers has been reflected in a number of liposome-based formulations, which are commercially available or are currently undergoing clinical trials. Also, novel lipid carrier-mediated vesicular systems are originated. This paper has focused on the lipid-based supramolecular vesicular carriers that are used in various drug delivery and drug targeting systems.