Looking into Task-Specific Activation Using a Prosthesis Substituting Vision with Audition

Table 2

Brain activation foci specific to experimental tasks using the sensory substitution device.

Brain area	Cluster size	𝑍 score	𝑥,𝑦,𝑧{mm}
Localization ∩ orientation
Right superior frontal gyrus (BA 8)	1095	5.98	10; 28; 50
Right superior frontal gyrus (BA 6)	(∗)	5.14	2; 22; 54
Right inferior frontal gyrus (BA 47)	258	5.67	38; 20; −6
Left superior parietal lobule/inferior parietal lobule (BA 7–40)	1073	5.50	−30; −50; 48
Left superior parietal lobule (BA 7)	(∗)	5.24	−40; −54; 50
Left precuneus/inferior parietal lobule (BA 7–40)	(∗)	5.18	−32; −70; 46
Left thalamus	984	5.34	−2; −32; 2
Left middle frontal gyrus (BA 9)	1014	5.07	−44; 6; 42
Right middle frontal gyrus (BA 9)	522	4.86	56; 22; 38
Left inferior frontal gyrus (BA 45)	367	4.36	−36; 24; 2
Localization > orientation
Right superior occipital gyrus/precuneus (BA 19–7)	179	4.69	42; −74; 34
Right angular gyrus (BA 39)	(∗)	3.37	54; −70; 36
Right inferior parietal lobule (BA 40)	(∗)	3.34	54; −68; 44
Right middle frontal gyrus (BA 6)	38	4.20	40; 6; 46
Right superior frontal gyrus (BA 6)	22	4.02	40; 24; 58
Right middle temporal gyrus (BA 21)	22	3.98	70; −42; −8
Right middle temporal gyrus (BA 19–39)	33	3.90	50; −74; 20
Right inferior frontal gyrus (BA 10–46)	14	3.73	48; 52; 2
Right superior parietal lobule (BA 7)	25	3.72	52; −60; 52
Right middle occipital gyrus (BA 19)	21	3.65	36; −80; 16
Right superior parietal lobule (BA 7)	11	3.55	8; −68; 62
Left middle temporal gyrus (BA 19–39)	17	3.38	−40; −80; 18

Overview of brain activation peaks in the contrasts {(SSD localization minus SSD control) conjunction (SSD orientation minus SSD control)} and {SSD localization minus SSD orientation masked (inclusive) by SSD localization minus rest}. Results are from a random-effect analysis, at 𝑃<0.05, FDR corrected, for the conjunction, and 𝑃<0.001 uncorrected, for the differential contrast between experimental tasks. Coordinates are reported in MNI space, as given by SPM2, and correspond only approximately to Talairach and Tournoux space [21]. BA: Brodmann area. (∗) belonging to the same voxels cluster.