Antenatal Corticosteroids for Late-Preterm Infants: A Decision-Analytic and Economic Analysis

Table 5

Number of cases of acute respiratory disease prevented and dollars saved through administration of ACS to hypothetical late-preterm birth cohort, assuming base-case estimates and late-preterm birth rate approximately 331,500 infants.

Strategy	Cases ARD; (𝑛)*	Cases ARD prevented; (𝑛)*	Cost saved; ($ millions)
34 weeks; ACS with labor	7072	7426	26.0
34 weeks; No ACS (Reference)	14498	Reference	Reference
35 weeks; ACS with labor	3536	3536	6.0
35 weeks; No ACS (Reference)	7072	Reference	Reference
36 weeks; ACS with labor	2122	1414	−3.4
36 weeks; No ACS (Reference)	3536	Reference	Reference

*Assumes that prevalence of late-preterm live singletons delivered annually (≈331,500) is divided equally between each gestational age week.
ACS: antenatal corticosteroids; ARD: acute respiratory disease.