Integrin Signaling in Mammary Epithelial Cells and Breast Cancer

Table 1

Targeted deletions of β1 integrin in the mammary gland.

Cre promoter	Phenotype	Reference
MMTV	No effect on early gland development	[29]
whey acidic protein (WAP)	Disorganized alevoli; inhibited luminal cell proliferation	[30]
β lactoglobulin (Blg)	Impaired alveolar morphogenesis and differentiation	[31]
keratin 5	Depletion of mammary stem cells; impaired regenerative potential	[32]