International Scholarly Research Notices / 2012 / Article / Tab 3

Research Article

Development and Validation of HPTLC Method for Estimation of Propranolol Hydrochloride and Flunarizine Dihydrochloride in Combined Dosage Form

Table 3

Robustness studies.

Method parameter/conditionDeliberate changes % RSD of peak area ( 𝑛 = 3 )

Chamber saturation time(a)20 min0.930.67
40 min1.130.98
Development distance from spot application(b)75 mm0.390.86
85 mm0.981.16

(a)±20% change in set time.
(b)±10% change in set distance.

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