An Approach to Visualize the Deformation of the Intermediate Filament Cytoskeleton in Response to Locally Applied Forces

Figure 7

Anisotropic deformation of the IF CSK. Contour maps of three flat cells experiencing a 20 nN indentation, with the central long axis of the cell labeled with a black line and the location of the AFM indentation labeled with an “x”. IF deformation tended to be focused away from the central longitudinal axis. Scale bar = 30 μm.