Assessment of Histopathological Response in Gastric and Gastro-Oesophageal Junction Adenocarcinoma following Neoadjuvant Chemotherapy: Which Scoring System to Use?

Table 2

Scoring grades and published studies with type of chemoradiotherapy used and level of completed response achieved.

Study	Chemotherapy	Radiotherapy	Patients	CR	Survival
Mandard et al. [7]	Cisplatin	37 Gy in 10 fractions of 3.7 Gy	93	18 (19%)	2-year OS 60%
Ninomiya et al. [10]	5-FU, leucovorin, etoposide,; cisplatin	—	18	0	2-year survival 28%
Becker et al. [11]	Etoposide, doxorubicin, cisplatin	—	36	0	5-year survival 27%
Lowy et al. [12]	5-FU	45 Gy in 25 fractions	19	2 (11%)	—
Ajani et al. [13]	5-FU, cisplatin, paclitaxel	45 Gy in 25 fractions of 1.8 Gy	41	8 (20%)	5-year survival in CR; 100%
Fareed et al. [14]	5-FU, cisplatin, epirubicin	—	45	2 (4%)	—

OS: overall survival; 5-FU: 5-fluorouracil; CR: complete response.