International Scholarly Research Notices / 2012 / Article / Fig 2

Research Article

miR-320 Regulates Glucose-Induced Gene Expression in Diabetes

Figure 2

HG caused increased (a) FN mRNA, (b) ET-1, and (c) VEGF expression by real-time RT-PCR in the HUVEC. HG-induced increased FN, ET-1, or VEGF mRNA expression was prevented following miR-320 mimic transfection. But not by scrambled (S) mimic transfection (HG: 25 mM D-glucose, LG: 5 mM D-glucose., 𝑃 < 0 . 0 5 compared to LG, mRNA levels expressed as a ratio to β-actin. OSM: 25 mM L-glucose, 𝜉 = 𝑃 < 0 . 0 5 compared to HG).

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