(R)-(+)-nicotine (+)-di-p-toluoyltartrate salt and (S)-(−)-nicotine Effect of homeopathic preparations of (R)-(+)-nicotine on [Ca2+]c response to 0.5% (S)-(−)-nicotine. Note: H1 and H2 homeopathic preparations. Underlined data represent statistically significant data according to the 5% LSD (least significant difference) where . This was only noted in the secondary endpoint Amplitude. Primary endpoint is final resting level (FRL).