Research Article
Characteristics and Prevalence of Latent Autoimmune Diabetes in Adults (LADA)
Table 1
Comparative evaluation of different parameters in different types of diabetes including LADA.
| Parameter | Type 1 | Type 2 | LADA | Undiagnosed |
| Prevalence (%) | 6.2 | 79.2 | 5 | 9.6 |
| Gender-wise prevalence | | | | | | | | | Males (%) | 38.7 | 62.12 | 80 | 54.16 | Females (%) | 61.3 | 37.87 | 20 | 45.83 |
| Average age (yrs) | | | | | Range (yrs) | 6–59 | 33–82 | 23–55 | 25–65 |
| Mean age at onset of diabetes (yrs) | | | | | Range (yrs) | 2–30 | 30–75 | 22–44 | 20–45 |
| Prevalence in different age groups (%) | M | F | M | F | M | F | M | F | <12 years | 16.66 | 10.52 | 0 | 0 | 0 | 0 | 0 | 0 | 12–24 years | 41.66 | 63.15 | 0 | 0 | 5 | 0 | 0 | 0 | 25–35 years | 16.66 | 26.31 | 0.8 | 0.8 | 15 | 20 | 11.5 | 36.36 | 36–45 years | 16.66 | 0 | 15.04 | 15.04 | 60 | 20 | 30.76 | 22.72 | >45 years | 8.33 | 0 | 54.14 | 84.14 | 20 | 60 | 57.69 | 40.90 |
| Family history (% patients) | | | | | | | | | Present | 35.48 | 57.07 | 52 | 70.81 | Absent | 65.42 | 42.93 | 48 | 29.17 |
| Basal metabolic index (BMI, % patients) | | | | | | | | | Underweight (U) | 38.6 | 1.76 | 12 | 5 | Healthy (H) | 58 | 25.5 | 76 | 55 | Overweight (H) | 3.2 | 47.3 | 12 | 35 | Obese (O) | 0 | 22.9 | 0 | 5 | Very obese (VOb) | 0 | 2.27 | 0 | 0 |
| Mean BMI | 19.96 ± 0.629 | 27.95 ± 0.26 | 22 ± 0.55 | 25.68 ± 0.65 | BMI range | 13.75–25 | 16–45 | 15–26 | 16.5–34 |
| Treatment regimen (% patients) | | | | | | | | | Insulin | 92.5 | 3.5 | 20 | 12 | OHA | 3.5 | 65.5 | 16 | 53.5 | Insulin + OHA | 3.5 | 29.5 | 60 | 34.5 |
| Drug therapy (% patients) | | | | | | | | | 1 DT | 96.4 | 18 | 23.6 | 28 | 2 DT | 3.6 | 28 | 23.8 | 28 | 3 DT | 0 | 29 | 23.8 | 12.5 | 4 DT | 0 | 21.5 | 28.5 | 22 | 5 DT | 0 | 3 | 0 | 9.4 |
| Mean HbA1c levels (%) | 9.661 ± 1.10 | 8.21 ± 0.25 | 10.45 ± 0.75 | 7.89 ± 0.47 |
| Mean cholesterol levels (mg/dL) | No data available | 181.96 ± 5.28 | 222.33 ± 26.87 | 210.90 ± 13.59 |
| Mean C-peptide levels (ng/mL) | 0.36 ± 0.05 | 1.26 ± 0.36 | 0.34 ± 0.05 | 0.63 ± 0.15 |
| GAD autoantibodies | 0.76 ± 0.05 | 0.7 ± 0.06 | 0.95 ± 0.06 | 1.01 ± 0.07 | (units/mL) | Absent | Absent | Present | Present |
|
|