Research Article
Antimicrobial or Subantimicrobial Antibiotic Therapy as an Adjunct to the Nonsurgical Periodontal Treatment: A Meta-Analysis
Table 2
Outcomes measured in systemic antibiotic treatment as an adjunctive therapy in scaling and root planing.
| Clinical and microbiological outcomes | Caton et al. 2000 [10] | Golub et al. 2001 [7] | Novak et al. 2002 [11] | Preshaw et al. 2004 [12] |
Preshaw et al. 2008 [18] | Guerrero et al. 2005 [14] | Reinhardt et al. 2007 [15] | Needleman et al. 2007 [16] | Griffiths et al. 2011 [17] |
| (1) CAL gain | * | * | * | * | * | * | * | * | * | (2) PD reduction | * | * | * | * | * | * | * | * | * | (3) % of BOP | * | | * | * | * | * | * | * | | (4) Adverse events | | | | * | | * | | | | (5) Gingival inflammation index | | * | * | | | | | | | (6) Plaque index | | | | | | | | | * | (7) Metabolic activity in GCF | | * | | | | | | * | | (8) Proportion of spirochetes | * | | | | | | | | | (9) Antibiotic sensitivity of microflora | | * | | | | | | | |
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CAL: clinical attachment level; PD: probing depth; BOP: bleeding on probing depth; metabolic activity in GCF gingival crevicular fluid.
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