Implementation of Quality by Design for the Development and Validation of Pioglitazone Hydrochloride by RP-UPLC with Application to Formulated Forms

Figure 7

Chromatograms obtained for forced degradation.

(a) 5% H₂O₂ degradation

(b) 5 N HCl degradation

(c) 5 N NaOH degradation

(d) H₂O degradation

(e) Thermal degradation

(f) Photolytic degradation