Research Article

Thyroid and Hepatic Haemodynamic Alterations among Egyptian Children with Liver Cirrhosis

Table 1

Comparison of Doppler haemodynamic parameters and thyroid function tests among cirrhotic patients and controls.

VariablePatients
( 𝑛 = 4 0 )
Controls
( 𝑛 = 3 0 )
𝑡 / 𝑧 # 𝑃

TV (mL) 7 . 9 ± 1 . 9
(3.3–13)
5 . 7 ± 0 . 3 9
(3.1–7.4)
2.60.042
TV SDS+ 2 . 8 ± 1 . 2
(+1.2 to +3.5)
+ 0 . 9 8 ± 0 . 4 8
(−0.5 to +1.63)
7.8*0.001
ITAPI 1 . 2 ± 0 . 4 2
(0.8–2.5)
0 . 7 8 ± 5 . 7
(0.7–0.9)
4.60.001
ITARI 0 . 7 8 ± 8 . 6
(0.63–0.77)
0 . 4 8 ± 2 . 1
(0.23–0.67)
7.10.041
f T 𝟑 (pg/mL) 1 . 9 ± 0 . 2
(1.4–2.4)
3 . 9 ± 1 . 0
(2.7–6)
4.80.001
f T 𝟒 (ng/dL) 1 . 6 ± 0 . 4
(0.8–2.3)
1 . 4 9 ± 0 . 5
(0.8–2.2)
0.70.4
TSH (mIU/mL) 4 . 0 5 ± 1 . 4
(1.7–7.5)
3 . 5 ± 1 . 4
(1.5–5.4)
1.040.3
HAPI 1 . 3 ± 0 . 4 6
(0.8–2.5)
0 . 7 4 ± 4 . 6
(0.68–0.81)
4.80.001
HARI 0 . 8 ± 8 . 2
(0.6–0.9)
0 . 3 2 ± 5 . 4
(0.55–0.71)
6.20.001

Results are expressed as mean ± SD or median and range, 𝑧 test#, 𝑃 < 0 . 0 5 *: significant, 𝑃 < 0 . 0 1 **: highly significant, 𝑃 > 0 . 0 5 : non-significant, TV: thyroid volume, TV SDS: thyroid volume standard deviation score, ITAPI: inferior thyroid artery pulsatility index, ITARI: inferior thyroid artery resistance index, f T 𝟑 : free triiodothyronine, f T 𝟒 : free tetraiodothyronine, TSH: thyroid stimulating hormone, HAPI: hepatic artery pulsatility index, HARI: hepatic artery resistance index.