Validated HPTLC Method for Simultaneous Estimation of Atenolol and Aspirin in Bulk Drug and Formulation

Table 1

Precision studies.

Concentration (ng/spot)	Repeatability (𝑛=6)			Intermediate precision (𝑛=6)
	Measured conc. ± SD	(%) RSD	Recovery (%)	Measured conc. ± SD	(%) RSD	Recovery (%)
Atenolol
200	198.78 ± 2.73	0.67	99.39	199.65 ± 3.89	1.14	99.82
400	400.05 ± 4.82	0.48	100.01	394.72 ± 5.20	0.68	98.68
600	599.31 ± 8.04	1.03	99.88	601.47 ± 7.95	0.70	100.24
Aspirin
200	196.61 ± 3.49	0.61	98.30	199.83 ± 3.94	0.69	99.91
400	398.32 ± 5.58	1.03	99.58	400.78 ± 5.83	0.83	100.19
600	601.77 ± 8.63	0.72	100.30	598.36 ± 8.17	1.04	99.72