Table of Contents
ISRN Emergency Medicine
Volume 2012 (2012), Article ID 624253, 5 pages
http://dx.doi.org/10.5402/2012/624253
Clinical Study

Clinical Profile and Outcomes of Hair Dye Poisoning in a Teaching Hospital in Nellore

1Narayana Medical College Hospital, Chinthareddypalem, Andhra Pradesh, Nellore 524002, India
2Department Of Clinical Pharmacology, 27/2/1334, Nellore, Balaji-Nagar 524002, India

Received 4 October 2011; Accepted 25 October 2011

Academic Editors: A. Banerjee, C. R. Harris, and Y. Kamijo

Copyright © 2012 Raghu Kondle et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Demographic profiles, volume consumed, time to hospitalization, clinical presentation, laboratory findings, treatment details, and outcomes of patients with hair dye poisoning were analyzed to assess the effect of Super Vasmol 33. The efficacy of methylprednisolone as compared to hydrocortisone in patients was also investigated. Findings show that there are significant differences in the clinical profiles laboratory markers such as markers of leukocytosis, rhabdomyolysis, and hepatitis among patients who consumed fewer volumes than larger volumes. Toxicity is dose dependent with increased morbidity and mortality. Consumption of even lower volumes resulted in hepatitis. For an apparently similar clinical and laboratory profile of patients, treatment with hydrocortisone is as effective as methylprednisolone in the clinical outcomes. These findings suggest that Super Vasmol 33 is emerging as a major source of poisoning.