Table of Contents
ISRN Endocrinology
Volume 2012 (2012), Article ID 630861, 6 pages
http://dx.doi.org/10.5402/2012/630861
Research Article

Study on Genetic Variance of miR-541 in Type 1 Diabetes

1Department of Endocrinology, Nanjing Children's Hospital Affiliated to Nanjing Medical University, Nanjing 210029, China
2Division of Biliary and Pancreatic Disease, Department of General Surgery, The 1st Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Nanjing 210029, China

Received 8 October 2012; Accepted 25 October 2012

Academic Editors: K. Yamagami and K. Zajickova

Copyright © 2012 Bei Han et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. Thomson, W. P. Robinson, M. K. Kuhner et al., “Genetic heterogeneity, modes of inheritance, and risk estimates for a joint study of caucasians with insulin-dependent diabetes mellitus,” American Journal of Human Genetics, vol. 43, no. 6, pp. 799–816, 1988. View at Google Scholar · View at Scopus
  2. C. E. Taplin and J. M. Barker, “Autoantibodies in type 1 diabetes,” Autoimmunity, vol. 41, no. 1, pp. 11–18, 2008. View at Publisher · View at Google Scholar · View at Scopus
  3. A. I. Tarasov, H. J. Welters, S. Senkel et al., “A Kir6.2 mutation causing neonatal diabetes impairs electrical activity and insulin secretion from INS-1 β-cells,” Diabetes, vol. 55, no. 11, pp. 3075–3082, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Esquela-Kerscher and F. J. Slack, “Oncomirs—microRNAs with a role in cancer,” Nature Reviews Cancer, vol. 6, no. 4, pp. 259–269, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. M. N. Poy, L. Eliasson, J. Krutzfeldt et al., “A pancreatic islet-specific microRNA regulates insulin secretion,” Nature, vol. 432, no. 7014, pp. 226–230, 2004. View at Publisher · View at Google Scholar · View at Scopus
  6. B. R. Gauthier and C. B. Wollheim, “MicroRNAs: ribo-regulators of glucose homeostasis,” Nature Medicine, vol. 12, no. 1, pp. 36–38, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. P. Skewes-Cox, Y. Kosaka, M. T. McManus, B. D. Harfe, M. S. German, and F. C. Lynn, “MicroRNA expression is required for pancreatic islet cell genesis in the mouse,” Diabetes, vol. 56, no. 12, pp. 2938–2945, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. M. V. Joglekar, V. M. Joglekar, and A. A. Hardikar, “Expression of islet-specific microRNAs during human pancreatic development,” Gene Expression Patterns, vol. 9, no. 2, pp. 109–113, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. A. He, L. Zhu, N. Gupta, Y. Chang, and F. Fang, “Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes,” Molecular Endocrinology, vol. 21, no. 11, pp. 2785–2794, 2007. View at Publisher · View at Google Scholar
  10. A. A. Teleman and S. M. Cohen, “Drosophila lacking microRNA miR-278 are defective in energy homeostasis,” Genes and Development, vol. 20, pp. 417–422, 2006. View at Google Scholar
  11. K. M. Pauley and E. K. L. Chan, “MicroRNAs and their emerging roles in immunology,” Annals of the New York Academy of Sciences, vol. 1143, pp. 226–239, 2008. View at Publisher · View at Google Scholar
  12. C. H. Bang-Berthelsen, L. Pedersen, T. Fløyel, P. H. Hagedorn, T. Gylvin, and F. Pociot, “Independent component and pathway-based analysis of miRNA-regulated gene expression in a model of type 1 diabetes,” BMC Genomics, vol. 12, article 97, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. G. A. Calin, M. Ferracin, A. Cimmino et al., “A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia,” New England Journal of Medicine, vol. 353, no. 17, pp. 1793–1801, 2005. View at Publisher · View at Google Scholar
  14. J. F. Abelson, K. Y. Kwan, B. J. O'Roak et al., “Sequence variants in SLITRK1 are associated with Tourette's syndrome,” Science, vol. 310, no. 5746, pp. 317–320, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. M. A. Saunders, H. Liang, and W. H. Li, “Human polymorphism at microRNAs and microRNA target sites,” Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 9, pp. 3300–3305, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. K. Chen and N. Rajewsky, “Natural selection on human microRNA binding sites inferred from SNP data,” Nature Genetics, vol. 38, no. 12, pp. 1452–1456, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. L. Zhou, H. He, J. X. Mi, C. Li, B. Lee, and Q. S. Mi, “MicroRNA genes,” Annals of the New York Academy of Sciences, vol. 1150, pp. 72–75, 2008. View at Google Scholar
  18. M. V. Joglekar, V. S. Parekh, and A. A. Hardikar, “New pancreas from old: microregulators of pancreas regeneration,” Trends in Endocrinology and Metabolism, vol. 18, no. 10, pp. 393–400, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. M. V. Joglekar, V. S. Parekh, S. Mehta, R. R. Bhonde, and A. A. Hardikar, “MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3,” Developmental Biology, vol. 311, no. 2, pp. 603–612, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. R. Madhyastha, H. Madhyastha, Y. Nakajima, S. Omura, and M. Maruyama, “MicroRNA signature in diabetic wound healing: promotive role of miR-21 in fibroblast migration,” International Wound Journal, vol. 9, no. 4, pp. 355–361, 2012. View at Publisher · View at Google Scholar
  21. J. Zhang, J. Zhang, L.-H. Liu et al., “Effects of miR-541 on neurite outgrowth during neuronal differentiation,” Cell Biochemistry and Function, vol. 29, no. 4, pp. 279–286, 2011. View at Publisher · View at Google Scholar