Research Article

I 𝟐 -SDS- H 𝟐 O System: A highly Efficient Dual Catalytic Green System for Deprotection of Imines and in Situ Preparation of Bis(indolyl)alkanes from Indoles in Water

Table 1

Optimization of the reaction conditionsa.


Entry
Reagent systemTime (h)Yieldsb (%)

1I2-SDS-H2O3.593
2I2-Triton X-H2O7.074
3I2-Aliquat 336-H2O8.072
4I2-CTAB-H2O6.369
5No catalyst24.0

aThe reactions were carried out using 1 mmol of 1,4-diphenyl-2,3-diaza-1,3-butadiene (1a) with 4 mmol of indole (2a) in presence of 15 mol% of I2 and 0.02 g of surfactant.
bIsolated yield.