Itraconazole Niosomes Drug Delivery System and Its Antimycotic Activity against Candida albicans

Table 4

Responses subjected to multiple regression analysis.

Response	Factorial batches
	ES60A	ES60B	ES60C	ES60D	ES60E	ES60F	ES60G	ES60H	ES60I
Vesicle size (μm) (Y1)	31.76	33.19	35.88	24.10	26.38	29.00	20.13	22.31	23.90
Entrapment efficiency (%) (Y2)	68.77	64.61	60.79	89.67	85.28	82.81	78.16	75.30	73.06
Time required for 50% drug release (hr) (Y3)	3.20	3.20	3.20	4.03	4.02	4.00	3.37	3.37	3.35