Emotion Processing in Women with Schizophrenia Is Menstrual Cycle Phase and Affective Valence Dependent: An fMRI Study

Table 6

Cerebral activations during processing of positive emotions in control and schizophrenia women during the follicular phase.

Anatomical area	L/R	Control women						Schizophrenia women
		BA	MNI coordinates			Z-score	Voxels	BA	MNI coordinates			Z-score	Voxels
			x	y	z				x	y	z
Fusiform	R	19	38	−49	−10	5.64	4702	18	24	−84	−14	5.91	4870
	L	37	−35	−46	−18	4.45	*	37	−38	−60	−18	5.70	*
Middle occipital	R	19	32	−94	14	5.45	*
	L	18	−21	−94	7	5.29	*	18	−24	−98	7	5.28	*
Superior occipital	L	17	−18	−91	4	5.29	*	18	−10	−102	7	5.68	*
	R	18	14	−94	18	4.98	*	18	18	−94	18	5.42	*
Inferior occipital	L	19	−46	−77	−4	5.29	*	19	−42	−80	−10	5.02	*
	R	19	38	−80	−4	4.93	*	19	35	−66	−10	4.93	*
Calcarine	L	18	−14	−74	4	4.87	*
	R	18	7	−77	4	4.85	*
Cuneus	R	18	14	−94	10	5.06	*
Cerebellum	R	—	18	−49	−18	4.78	*	—	35	−46	−24	5.03	*
Inferior temporal	L	37	−42	−63	−10	4.55	*
Parahippocampal	R	35	21	−35	−10	4.06	*
Thalamus	L							—	−21	−28	0	3.82	40
Pallidum	L							—	−21	−7	−7	3.58	13
Postcentral	L	2	−46	−35	60	4.69	433
Superior parietal	L							7	−28	−60	49	4.20	4870
Inferior parietal	L	2	−56	−24	46	4.13	*
Supramarginal	R							40	38	−35	42	3.23	8
Precentral	R	8	56	10	42	4.59	302	9	52	4	28	3.97	68
Inferior frontal	R	44	63	18	14	4.27	*
	L	13	−38	14	18	3.78	26
Medial OFC	R							11	7	52	−10	3.40	18
Inferior OFC	L							47	−28	28	−14	3.32	15
Superior medial frontal	L	9	−4	56	32	3.37	25
SMA	L	32	−4	7	52	3.85	114	6	−4	0	56	3.76	41
		Controls greater than patients						Patients greater than controls
Superior temporal	R	13	46	−46	21	3.29	17
Cerebellum	L	—	−24	−35	−35	3.19	29
	R	—	24	−32	−32	3.00	91
Calcarine	L	30	−10	−66	10	3.17	139

L: left; R: right; BA: Brodmann area; SMA: supplementary motor area; OFC: orbitofrontal cortex; P uncorrected ≤0.001.