Emotion Processing in Women with Schizophrenia Is Menstrual Cycle Phase and Affective Valence Dependent: An fMRI Study

Table 7

Cerebral activations during processing of positive emotions in control and schizophrenia women during the luteal phase.

Anatomical area	L/R	Control women						Schizophrenia women
		BA	MNI coordinates			Z-score	Voxels	BA	MNI coordinates			Z-score	Voxels
			x	y	z				x	y	z
Fusiform	R	19	32	−52	−10	5.76	8191
	L							19	−38	−70	−18	6.33	4076
Middle occipital	L	17	−10	−94	0	6.23	*	18	−24	−94	7	5.76	*
Inferior occipital	R	19	42	−80	−4	6.16	*
	L							18	−49	−80	−7	6.16	*
Hippocampus	R	—	18	−35	0	5.22	*
Posterior cingulate	R	29	10	−42	7	5.01	*
Cerebellum	R	—	14	−52	−49	3.49	*	—	4	−74	−38	3.77	4076
Postcentral	L							40	−38	−35	46	4.40	90
Supramarginal	L							3	−56	−24	42	3.30	*
Precentral	L							6	−38	−10	52	3.73	30
	R							6	42	−7	49	3.30	6
Inferior frontal	R	9	38	7	24	5.46	480	9	56	7	28	3.41	34
Medial frontal	L	10	−7	63	24	4.04	35
Inferior OFC	R	11	28	35	−10	3.48	8
Superior frontal	R	6	35	−4	66	3.31	7
SMA	L	32	−7	7	46	3.66	96	6	0	4	60	3.67	33
		Controls greater than patients						Patients greater than controls
Posterior cingulate	R	29	7	−42	10	3.55	106
Calcarine	L	30	−21	−52	10	3.41	*
Precuneus	R	30	21	−46	7	3.36	*

L: left; R: right; BA: Brodmann area; SMA: supplementary motor area; OFC: orbitofrontal cortex; P uncorrected ≤0.001.