Endoscopic Submucosal Dissection for Treatment of Patients Aged 75 Years and over with Esophageal Cancer

Table 3

Treatment results.

	≥75 years (𝑛=13)	<75 years (𝑛=49)	P value
Area of specimen (cm^2 : median, range)	6.9 (3.9–8.0)	6.6 (1.3–23.8)	n.s.
Procedure time (min : median, range)	107 (54–187)	127 (42–485)	n.s.
CO2 insufflation used	10 (77%)	24 (49%)	n.s.
Depth of tumor invasion			n.s.
m1-m2	11	33
m3-sm1	2	12
sm2	0	4
Horizontal margin			n.s.
pHM0	12	45
pHMXor1	1	4
Vertical margin			n.s.
pVM0	13	49
pVMXor1	0	0
Complete resection	12 (92%)	44 (90%)	n.s.
Curative resection	10 (77%)	29 (59%)	n.s.

m1: intraepithelial carcinoma; m2: microinvasive carcinoma (invasion through the basement membrane); m3: intramucosal carcinoma (invasion to the muscularis mucosae); sm1: superficial invasion in the submucosa (extended up to 200 mm below the lower border of the lamina muscularis mucosae); sm2: deep invasion in the submucosa (deeper than 200 mm below the lower border of the lamina muscularis).
complete resection: en bloc resection with tumor-free margins; curative resection: complete resection with depth of m1 or m2 and without lymphatic or venous invasion.
n.s.=not significant.