Organ-Tissue Level Model of Resting Energy Expenditure Across Mammals: New Insights into Kleiber's Law

Table 1

Estimated 𝐾 values of organ-tissue level components across mature mammals.

Species	𝑀	𝐾𝐿	𝐾𝐵	𝐾𝐻	𝐾𝐾	𝐾𝑅
Rat	0.48	870	470	968	685	33.7
Rabbit	2.5	590	—	—	—	—
Cat	3.0	420	—	—	—	—
Dog	10	380	370	—	679	—
Human	65	251	230	668	482	20.7
Human	70	200	240	440	440	10.7
𝐾𝑖=𝑎×𝑀^𝑏
Coefficient a		683.9	446.6	890.3	689.7	29.96
Scaling; exponent 𝑏		−0.2677	−0.1423	−0.1181	−0.0833	−0.1667
𝑃 value		0.975	0.961	0.855	0.848	0.827

Source of 𝐾 data. Rat [5], rabbit, cat, dog [6], and human [7, 8]. Specific resting metabolic rates for liver, brain, heart, and kidneys of various mammals are consistent with results given by the above references. Specific resting metabolic rates for the residuals are calculated from the above references.
Abbreviations: 𝑀: body mass (in kg); 𝐾𝐿,𝐾𝐵,𝐾𝐻,𝐾𝐾,and  𝐾𝑅: specific resting metabolic rate of liver, brain, heart, kidney, and residuals, respectively (all in kcal/kg per day).