Research Article
Cyclin A2 Protein Overexpression Is Not Caused by Gene Amplification in Colon Cancer
Table 2
CCNA2 amplification in tumour cells and in total tumour in breast cancer tissue compared to normal tissue, as well as fluorescence in situ hybridization data in tumour tissue and in normal tissue.
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, where ΔΔCt = ( − Ctendogenous controls) − ( − Ctendogenous controls). bChromosome aberration was measured by fluorescence in situ hybridization counting cyclin A2 and centromere 4 signals in nuclei within tumour areas and normal mucosa. The average number of cyclin A2 and centromere 4 signals per nucleus are indicated both in tumour and normal tissue. |