C3b-Independent Complement Activation in Ischemia/Reperfusion Mesenteric Tissue Injury in Autoimmune Prone (B6.MRL/lpr) Mice
Figure 5
Complement C3-independent tissue injury pathway. A schematic, which depicts a possible alternative interaction between the complement cascade and coagulation cascade, is presented. The cartoon diagrams a possible explanation of the data presented, specifically how the C3 component of the complement cascade can be bypassed to produce activated C5a.