Increased Phospho-Keratin 8 Isoforms in Colorectal Tumors Associated with EGFR Pathway Activation and Reduced Apoptosis
Figure 2
Levels of K8 phospho-isoforms determined by western blotting. (a) Plots showing abundance levels of PS24, PS432, and PS74 normalised to β actin loading control and total K8 in 30 matched pairs of tumor-normal tissues. (b) A representative western blot of total K8, β actin and PS432. In the case of multiple bands, all bands were included in quantification. Tumor (T) and normal (N) pairs were loaded in adjacent lanes from left to right. Statistical analysis was performed using a 2-tailed Wilcoxon matched pairs test.
