The Toxic Effects of Polychemotherapy onto the Liver Are Accelerated by the Upregulated MDR of Lymphosarcoma

Figure 2

Expression levels of mdr1a (a, b), mdr1b (a, b), bcl-2 (c, d), and p53 (c, d) genes in cells of primary culture RLS₄₀ after the treatment of tumor-bearing animals, according to Scheme 1 and Scheme 2. Separation of RT-PCR products in 8% PAAG and quantification of the band intensities are shown.

(a)

(b)

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(d)