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ISRN Biochemistry
Volume 2012 (2012), Article ID 728571, 12 pages
Review Article

Calpain Dysregulation in Alzheimer’s Disease

Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Avenue, Ward 8-140, Chicago, IL 60611, USA

Received 26 August 2012; Accepted 12 September 2012

Academic Editors: A. Caceres and B. Lenarcic

Copyright © 2012 Adriana Ferreira. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [11 citations]

The following is the list of published articles that have cited the current article.

  • MaryKate McBrayer, and Ralph A. Nixon, “Lysosome and calcium dysregulation in Alzheimer's disease: partners in crime,” Biochemical Society Transactions, vol. 41, pp. 1495–1502, 2013. View at Publisher · View at Google Scholar
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  • Tatyana Gurlo, Safia Costes, Jonathan D. Hoang, Jacqueline F. Rivera, Alexandra E. Butler, and Peter C. Butler, “β Cell–specific increased expression of calpastatin prevents diabetes induced by islet amyloid polypeptide toxicity,” JCI Insight, vol. 1, no. 18, 2016. View at Publisher · View at Google Scholar
  • Zeinab ElHajj, Amélie Cachot, Terry Müller, Irène M. Riederer, and Beat M. Riederer, “Effects of postmortem delays on protein composition and oxidation,” Brain Research Bulletin, 2016. View at Publisher · View at Google Scholar
  • Andreas Kling, Katja Jantos, Helmut Mack, Wilfried Hornberger, Karla Drescher, Volker Nimmrich, Ana Relo, Karsten Wicke, Charles W. Hutchins, Yanbin Lao, Kennan C Marsh, and Achim Moeller, “Discovery of Novel and Highly Selective Inhibitors of Calpain for the Treatment of Alzheimer´s Disease: 2-(3-Phenyl-1H-pyrazol-1-yl)nicotinamides,” Journal of Medicinal Chemistry, 2017. View at Publisher · View at Google Scholar
  • Franc Llorens, Katrin Thüne, Beata Sikorska, Matthias Schmitz, Waqas Tahir, Natalia Fernández-Borges, Maria Cramm, Nadine Gotzmann, Margarita Carmona, Nathalie Streichenberger, Uwe Michel, Saima Zafar, Anna-Lena Schuetz, Ashish Rajput, Olivier Andréoletti, Stefan Bonn, Andre Fischer, Pawel P. Liberski, Juan Maria Torres, Isidre Ferrer, and Inga Zerr, “Altered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob disease,” Acta Neuropathologica Communications, vol. 5, no. 1, 2017. View at Publisher · View at Google Scholar