Spectrophotometric Estimation of Flutamide in Pure and in Pharmaceutical Preparations

Table 3

Results of determination of FA in tablets and statistical comparison with the reference method.

Tablet brand name	Nominal amount; mg per tablet	Found** (% of nominal amount ± SD)
		Reference method [13]	Method A	Method B	Method C
CYTOMID^a	250 mg	100.22 ± 0.62	100.31 ± 0.406; 𝑡=0.136,; 𝐹=2.34	101.02 ± 0.398; 𝑡=1.247,; 𝐹=2.43	100.46 ± 0.382; 𝑡=0.689,; 𝐹=3.05
DROGENIL^b	250 mg	100.22 ± 0.62	99.64 ± 0.317; 𝑡=0.971,; 𝐹=3.83	100.87 ± 0.288; 𝑡=1.134,; 𝐹=4.63	100.60 ± 0.399; 𝑡=0.591,; 𝐹=2.42

Marketed by: ^aCipla (Pvt) Ltd; ^bFulford.
**Mean value of five determinations.
Tabulated 𝑡 and 𝐹-values at 95 % confidence level are 2.77 and 6.39, respectively.