Not All Critically Ill Obese Patients Are the Same: The Influence of Prior Comorbidities

Table 1

Studies examining mortality in obese critically ill patients and the adjustments for co-morbid illness.

Author	BMI of obese patients and no.	Study design	Findings	Adjustments for co-morbidity in multivariate analysis
Ray et al. (2005) [3]	BMI ≥ 30, 𝑛=237	Retrospective.; (ALI patients)	No mortality difference.	APACHE II only
Frat et al. (2008) [6]	BM ≥ 35, 𝑛=121	Matching.	No mortality difference with obesity but difficulty with intubation and stridor.	SAPS II only
Sakr et al. (2008) [4]	BMI ≥ 30, 𝑛=505	Retrospective.	No difference in mortality in but increased LOS.	SAPS II; Cancer, CHF, COPD, and DM
Aldawood et al. (2006) [2]	BMI ≥ 30, 𝑛=971	Retrospective.	Lower mortality.	APACHE II; Chronic respiratory illness.
O'Brien et al. (2006) [5]	BMI ≥ 30, 𝑛=458	Retrospective.; (ALI patients)	Lower mortality.	SAPS II only
Garrouste-Orgeas et al. (2004); [7]	BMI ≥ 30, 𝑛=232	Retrospective.; (surgical patients)	No mortality difference.	APACHE II only
Memtsoudis et al. (2012) [8]	BMI ≥ 30	Retrospective.; (surgical/ARDS)	Lower mortality in obese patients.	Deyo co-morbidity index
Martino et al. (2011) [10]	BMI ≥ 40, 𝑛=524	Retrospective.; (nutrition survey)	No mortality difference with obesity but longer time on mechanical ventilation and in ICU.	APACHE II only