Table of Contents
ISRN Dentistry
Volume 2012, Article ID 762095, 6 pages
Review Article

Tissue Reactions to Various Suture Materials Used in Oral Surgical Interventions

1Engineer Abdullah Bugshan Research Chair for Growth Factors and Bone Regeneration, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia
2Department of Periodontics and Community Dentistry, King Saud University, Riyadh 11545, Saudi Arabia
3Division of Periodontology, University of Connecticut, Farmington, CT 06032, USA
4Division of Periodontology, Eastman Institute for Oral Health, University of Rochester, Rochester, NY 14620, USA

Received 22 December 2011; Accepted 19 February 2012

Academic Editor: P. Gjermo

Copyright © 2012 Fawad Javed et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A variety of suture materials are available for primary wound closure following oral surgical procedures. The aim was to review the tissue reactions to the various suture materials used in oral surgical interventions. Databases were searched using the following keywords: cotton, nylon, polyglecaprone 25, polytetrafluoroethylene (ePTFE), Polyglactin 910, polyglycolic acid (PGA), polylactic acid, silk, surgery, suture, and tissue reaction. Articles published only in English language were included. Seventeen studies were included. Two studies reported that polyglecaprone 25 had positive effects on wound-healing as compared to silk. Six studies reported that silk elicits more intense tissue inflammatory response and delayed wound healing as compared to other suture materials (including ePTFE, polyglecaprone-25, PGA, and nylon). Polyglactin 910 sutures were associated with the development of stitch abscess in one clinical study. Eight studies reported that tissue reactions are minimal with nylon sutures. Tissue reactions to suture materials used for oral surgical interventions may vary depending on the surface properties and bacterial adherence properties of the material.