Nuclear Magnetic Resonance Spectroscopy in the Detection and Characterisation of Cardiovascular Disease: Key Studies

Figure 2

A typical metabolomics procedure requires data acquisition using a suitable technique, data reduction and finally multivariate analysis (MVA) to interrogate the sample data. For this example, human blood plasma is analysed using NMR spectroscopy followed by binning as the data reduction method. Principal components analysis (PCA) is the MVA employed producing a scores plot and a loadings plot which can be used to identify trends across the set of patients.